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MYP_005301
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Basic Information
RNase 3
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
133 amino acids
C677H1064N224O184S9
Standard
Sequence
RPPQFTRAQWFAIQHISLNPPRCTIAMRAINNYRWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNISNCRYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI
Physicochemical Analysis
15573.67 Da
10.72
14.12
13.53
0.1062
-0.63
0.94
-0.20
62.29
69.62
0.0902
16960.00
17460.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
6648.74
-75.46
239.0
212.0
490.0
1094.0
31.0
153.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0119736 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecium
0.90±0.14 μM
MBC
PMID27089320 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27089320/
RECORD: Rec_0238382 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
0.20±0.01 μM
MBC
PMID27089320 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27089320/
RECORD: Rec_0255386 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
A. baumanii
0.40±0.03 μM
MBC
PMID27089320 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27089320/
RECORD: Rec_0263066 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Sheep red blood cells
20 μM
HC50
PMID27089320 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27089320/
RECORD: Rec_0266892 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
0.35±0.02 μM
MBC
PMID27089320 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27089320/
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