Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length264 amino acids

Chemical FormulaC1343H2101N339O391S6

DescriptionStandard

        MEKPILKNLNEMLCPIIMNEVEALNANLSTIEVLTKIDNYTLLDYSLISSPEITENYINLNLKGVVYPLEDLTDPPFSPVPFVLPERSDSMLYVGISEFFFKSASFAYFTAGAFNVTLSTKEISNHLVQNSQGVGNVLSRVASTSVGLVILGQRLVCSLSLNRFRLSLPESNRSNIEVLRFENILSSILHFGILPLANAKLQQGFPLPNPHKISFVNSDIEVFEGFLLISTDLKYETSLKQQPSFHGWEGLNFINGQWRGKPAA
    

Molecular Weight29444.47 Da

Isoelectric Point (pI)5.29

Net Charge (pH 7.0)-6.13

Net Charge (pH 7.4) -6.64

Charge Density (pH 7.0) -0.0232

GRAVY Index0.10

Hydrophobic Moment 0.63

Boman Index0.15

Instability Index45.10

Aliphatic Index 106.67

Aromaticity 0.0985

Extinction Coeff. Reduced 21430.00

Extinction Coeff. Oxidized 21555.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0418460 VERIFIED: NO

Provenance & Taxonomy

OrganismLynx canadensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria