Peptide Database

Peptide NameDermaseptin K4S4

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antiviral

Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC133H232N36O32

DescriptionStandard

        ALWKTLLKKVLKAAAKAALNAVLVGANA
    

Molecular Weight2847.49 Da

Isoelectric Point (pI)10.60

Net Charge (pH 7.0)4.79

Net Charge (pH 7.4) 4.60

Charge Density (pH 7.0) 0.1711

GRAVY Index0.82

Hydrophobic Moment 0.71

Boman Index0.26

Instability Index2.94

Aliphatic Index 146.79

Aromaticity 0.0357

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1101.32

LogP -6.96

H-bond Donors 38.0

H-bond Acceptors 37.0

Rotatable Bonds 97.0

Heavy Atoms 201.0

Ring Count 2.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0423718 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDermaseptin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral Cytotoxic

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