Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC364H577N105O88S8

DescriptionStandard

        MKIHLFFFILLFWVTILPARKKYPHYGSLDLRRECRKGNGRCKLECQENEIRIAYCMRPATHCCLQK
    

Molecular Weight8088.65 Da

Isoelectric Point (pI)9.54

Net Charge (pH 7.0)7.71

Net Charge (pH 7.4) 7.23

Charge Density (pH 7.0) 0.1150

GRAVY Index-0.25

Hydrophobic Moment 0.59

Boman Index-0.09

Instability Index66.87

Aliphatic Index 84.48

Aromaticity 0.1194

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3129.04

LogP -20.77

H-bond Donors 117.0

H-bond Acceptors 107.0

Rotatable Bonds 270.0

Heavy Atoms 565.0

Ring Count 15.0

Amide Bonds 70.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0353047 VERIFIED: NO

Provenance & Taxonomy

OrganismLynx pardinus [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence