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MYP_005227
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Basic Information
Crotamine (30-39)
Antimicrobial
Antimicrobial ▸ Antibacterial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Standard
10 amino acids
C61H97N21O11S3
Standard
Sequence
CRWRWKCCKK
Physicochemical Analysis
1396.75 Da
9.90
4.73
4.48
0.4727
-1.50
0.34
-0.71
123.56
0.00
0.2000
11000.00
11125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
558.66
-3.09
25.0
19.0
46.0
96.0
4.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0129293 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Candida albicans MTCC 227
40 μM
MIC
PMID27836642 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27836642/
RECORD: Rec_0134164 VERIFIED: YES
Provenance & Taxonomy
Crotalus durissus terrificus [Animal]
Crotamine/CyLoP-1
8732
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Fluorescein/FITC labeling
None
N-term detail: Labelled with K-FITC or k-FITC at N-terminus; lowercase source residues at positions 2 denote stereochemical modification
Bio-Activity Profile
Cell-penetrating peptide
NIH-3T3
Fluorescence-based uptake assay
PMID21319732 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319732/
RECORD: Rec_0150039 VERIFIED: YES
Provenance & Taxonomy
Crotalus durissus terrificus [Animal]
Crotamine/CyLoP-1
8732
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Fluorescein/FITC labeling
None
N-term detail: Labelled with K-FITC or k-FITC at N-terminus; lowercase source residues at positions 2,3,4,5 denote stereochemical modification
Bio-Activity Profile
Cell-penetrating peptide
NIH-3T3
Fluorescence-based uptake assay
PMID21319732 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319732/
RECORD: Rec_0174719 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Salmonella typhi
10 μM
MIC
PMID27836642 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27836642/
RECORD: Rec_0180671 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human cervical carcinoma HeLa
40 μM
PMID27836642 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27836642/
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