Peptide Database

Peptide NameBeta defensin 2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length44 amino acids

Chemical FormulaC208H338N62O54S6

DescriptionStandard

        VFGDISNPVTCLRSGAICHPGFCPRRYKHIGTCGLSVIKCCKKP
    

Molecular Weight4763.68 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)5.84

Net Charge (pH 7.4) 5.44

Charge Density (pH 7.0) 0.1328

GRAVY Index0.10

Hydrophobic Moment 0.48

Boman Index0.05

Instability Index53.51

Aliphatic Index 75.23

Aromaticity 0.0682

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1828.37

LogP -18.97

H-bond Donors 70.0

H-bond Acceptors 68.0

Rotatable Bonds 151.0

Heavy Atoms 330.0

Ring Count 9.0

Amide Bonds 44.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0133137 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo pygmaeus [Animal]

FamilyDefensin

Tax ID9600

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal