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MYP_005162
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Basic Information
Pentobra
Antimicrobial
Standard
12 amino acids
C81H123N27O16
Standard
Sequence
RQIKIWFQNRRW
Physicochemical Analysis
1731.01 Da
12.00
3.76
3.55
0.3133
-1.49
0.38
-0.50
106.53
65.00
0.2500
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
755.99
-4.16
28.0
20.0
57.0
124.0
5.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0208381 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
N-terminal tobramycin conjugation
Tobramycin conjugate; N-terminal conjugation
Bio-Activity Profile
Antimicrobial
PaperDesigning Hybrid Antibiotic Peptide Conjugates To Cross Bacterial Membranes PMID28248495 Evidence URLhttps://doi.org/10.1021/acs.bioconjchem.6b00725 PatentUS20170348337A1
RECORD: Rec_0431498 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
N-terminal tobramycin conjugation
Tobramycin conjugate; N-terminal conjugation
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli (mid-log phase)
6.25 μM
MIC
PaperDesigning Hybrid Antibiotic Peptide Conjugates To Cross Bacterial Membranes PMID28248495 PatentUS20170348337A1
RECORD: Rec_0431499 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
N-terminal tobramycin conjugation
Tobramycin conjugate; N-terminal conjugation
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa (mid-log phase)
6.25-12.5 μM
MIC
PaperDesigning Hybrid Antibiotic Peptide Conjugates To Cross Bacterial Membranes PMID28248495 PatentUS20170348337A1
RECORD: Rec_0431500 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
N-terminal tobramycin conjugation
Tobramycin conjugate; N-terminal conjugation
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa (stationary phase)
25 μM
MIC
PaperDesigning Hybrid Antibiotic Peptide Conjugates To Cross Bacterial Membranes PMID28248495 PatentUS20170348337A1
RECORD: Rec_0431501 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
N-terminal tobramycin conjugation
Tobramycin conjugate; N-terminal conjugation
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus (mid-log phase)
25 μM
MIC
PaperDesigning Hybrid Antibiotic Peptide Conjugates To Cross Bacterial Membranes PMID28248495 PatentUS20170348337A1