Peptide Database

Peptide Name[Leu31,Pro34]NPY

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC193H291N53O54S

DescriptionStandard

        YPLKPPNPGEDAPAEDMARYYSALRHYINLLTRPRY
    

Molecular Weight4249.76 Da

Isoelectric Point (pI)8.34

Net Charge (pH 7.0)0.85

Net Charge (pH 7.4) 0.58

Charge Density (pH 7.0) 0.0236

GRAVY Index-0.98

Hydrophobic Moment 0.70

Boman Index-0.16

Instability Index61.38

Aliphatic Index 65.28

Aromaticity 0.1389

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1708.37

LogP -13.21

H-bond Donors 58.0

H-bond Acceptors 57.0

Rotatable Bonds 126.0

Heavy Atoms 301.0

Ring Count 12.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0101342 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Signaling peptide

TargetY1 receptor (Human); Y1 receptor (Rat); Y2 receptor (Human)

Activity78.7 nM

MethodEC50