MYP_005111
Basic Information
Reteplase
Hemostasis Anticoagulant activity
Hemostasis Fibrinolytic activity
Therapeutic / Biomedical activity Enzyme replacement therapy
Standard
355 amino acids
C1736H2671N499O522S22
Standard
Sequence
SYQGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCSTCGLRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMRP
Physicochemical Analysis
39589.24 Da
6.86
-0.55
-1.76
-0.0015
-0.43
0.66
-0.03
46.59
72.25
0.0930
66350.00
67475.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0017041 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]; Chinese hamster ovary cell line [Animal]
Growth factor
9606; 10029
Structure & Mods
single-chain therapeutic peptide/protein [Linear]
canonical L-amino-acid peptide [L]
Glycosylation
Bio-Activity Profile
Enzyme replacement Anticoagulant Thrombolytic Fibrinolytic
CHO
RECORD: Rec_0204673 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]; Chinese hamster ovary cell line [Animal]
Growth factor
9606; 10029
Structure & Mods
single-chain therapeutic peptide/protein [Linear]
canonical L-amino-acid peptide [L]
Glycosylation, Phosphorylation
Bio-Activity Profile
Enzyme replacement Anticoagulant Thrombolytic Fibrinolytic
CHO