Peptide Database

Peptide NamePreprocathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length138 amino acids

Chemical FormulaC694H1130N194O199S5

DescriptionStandard

        SLWLLLLGLALPSASAQALSYREAVLRAVDQFNERSSEANLYRLLELDPPPKEDDENPNIPKPVSFRVKETVCPRTSQQPAEQCDFKENGLVKQCVGTVTLDAVKGKMNVTCKGLQSVGRFKRFRKKFKKLFKKLSPV
    

Molecular Weight15535.90 Da

Isoelectric Point (pI)9.59

Net Charge (pH 7.0)8.44

Net Charge (pH 7.4) 8.13

Charge Density (pH 7.0) 0.0611

GRAVY Index-0.43

Hydrophobic Moment 0.82

Boman Index-0.11

Instability Index37.79

Aliphatic Index 85.43

Aromaticity 0.0725

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6388.89

LogP -61.74

H-bond Donors 221.0

H-bond Acceptors 213.0

Rotatable Bonds 525.0

Heavy Atoms 1092.0

Ring Count 21.0

Amide Bonds 150.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0067332 VERIFIED: NO

Provenance & Taxonomy

OrganismBos indicus [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence