Peptide Database

Peptide NameRugosin-RN antimicrobial peptide

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC366H597N91O119S6

DescriptionStandard

        MFTMKKSLLLLFFLGTISLSLCEEERGADEDDGEEMTEEEVKRSFLSKFKDIALDVAKNAGKGVLTTLACKIDGSC
    

Molecular Weight8368.58 Da

Isoelectric Point (pI)4.62

Net Charge (pH 7.0)-5.51

Net Charge (pH 7.4) -5.80

Charge Density (pH 7.0) -0.0724

GRAVY Index-0.04

Hydrophobic Moment 0.65

Boman Index0.03

Instability Index44.98

Aliphatic Index 89.87

Aromaticity 0.0658

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3402.90

LogP -31.56

H-bond Donors 121.0

H-bond Acceptors 120.0

Rotatable Bonds 296.0

Heavy Atoms 582.0

Ring Count 5.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0010282 VERIFIED: NO

Provenance & Taxonomy

OrganismRana nigrovittata [Animal]

FamilyRugosin

Tax ID127021

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0062952 VERIFIED: NO

Provenance & Taxonomy

OrganismSylvirana [Animal]

Tax ID1659747

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal