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MYP_005065
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Basic Information
Glucagon-like peptide 1
Hormonal / Endocrine ▸ Hormone peptide
Metabolic
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
37 amino acids
C186H275N51O59
Standard
Sequence
HDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG
Physicochemical Analysis
4169.48 Da
5.05
-3.05
-3.37
-0.0825
-0.61
0.51
-0.03
19.15
58.11
0.1351
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1785.48
-17.70
63.0
58.0
138.0
296.0
8.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0332510 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0341044 VERIFIED: NO
Provenance & Taxonomy
Canis familiaris [Animal]
Glucagon
9615
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Arg36 Amidation
Bio-Activity Profile
Hormone Metabolic
Evidence URLhttps://www.uniprot.org/uniprotkb/GLUC_CANFA/entry
RECORD: Rec_0356785 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
Glucagon
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Arg36 Amidation
Bio-Activity Profile
Hormone Metabolic
Evidence URLhttps://www.uniprot.org/uniprotkb/GLUC_RAT/entry
RECORD: Rec_0393513 VERIFIED: NO
Provenance & Taxonomy
Sus scrofa [Animal]
Glucagon
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Arg36 Amidation
Bio-Activity Profile
Hormone Metabolic
Evidence URLhttps://www.uniprot.org/uniprotkb/GLUC_PIG/entry
RECORD: Rec_0396838 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Glucagon-like peptide
9606
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
14:Phosphoserine; 17:Phosphoserine; 36:Arginine amide
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation Feeding regulator
peripheral tissue
Experimental: <5 minutes; /300 seconds; Mammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Glucagon-like peptide 1 (Homo sapiens): PMID 15664668##17283237 PMID15664668;17283237 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15664668/
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