Peptide Database

Peptide NameUnnamed

Function Ontology

Anticancer

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC150H222N38O48S3

DescriptionStandard

        LHCPALVTYNTDTFESMPNPEGRYTFGASCV
    

Molecular Weight3421.79 Da

Isoelectric Point (pI)4.65

Net Charge (pH 7.0)-2.17

Net Charge (pH 7.4) -2.46

Charge Density (pH 7.0) -0.0699

GRAVY Index-0.18

Hydrophobic Moment 0.42

Boman Index0.11

Instability Index44.98

Aliphatic Index 50.32

Aromaticity 0.1290

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1360.45

LogP -15.15

H-bond Donors 48.0

H-bond Acceptors 50.0

Rotatable Bonds 101.0

Heavy Atoms 239.0

Ring Count 8.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0003309 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Anticancer

RECORD: Rec_0132179 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyHER2/VEGF mimetic

Tax ID32630

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide3-30

Other ModsCyclized CYC construct reported in literature.

Bio-Activity Profile

Function

Anti-angiogenic Anticancer

TargetEndothelial cells / tumor model

Methodtumor model

RECORD: Rec_0245304 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyHER2/VEGF mimetic

Tax ID32630

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide3-30

Other ModsCyclized CYC construct reported in literature.

Bio-Activity Profile

Function

Anti-angiogenic Anticancer

TargetEndothelial cells / tumor model

MethodEndothelial proliferation assay

RECORD: Rec_0320492 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyHER2/VEGF mimetic

Tax ID32630

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide3-30

Other ModsCyclized CYC construct reported in literature.

Bio-Activity Profile

Function

Anti-angiogenic Anticancer

TargetEndothelial cells / tumor model

MethodMigration assay

RECORD: Rec_0415694 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Anticancer Anti-angiogenic