Peptide Database

Peptide NameChimeric ANP-C

Function Ontology

Regulator of sodium ions in heart

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC188H309N63O53S3

DescriptionStandard

        RPQLKAPPKKSEKRQQVCFGGRMDRIGAQSGLGCNSFRY
    

Molecular Weight4396.05 Da

Isoelectric Point (pI)10.54

Net Charge (pH 7.0)6.74

Net Charge (pH 7.4) 6.50

Charge Density (pH 7.0) 0.1728

GRAVY Index-1.04

Hydrophobic Moment 0.54

Boman Index-0.32

Instability Index56.95

Aliphatic Index 42.56

Aromaticity 0.0769

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1927.30

LogP -23.54

H-bond Donors 69.0

H-bond Acceptors 63.0

Rotatable Bonds 150.0

Heavy Atoms 307.0

Ring Count 6.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0423795 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyNatriuretic peptide

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide18-34

Bio-Activity Profile

Function

Regulator of sodium ions in heart

MethodCompetitive Radioimmunoassay

Half-LifeRat plasma (Subcutaneous), in vivo; 2268 s