MYP_004938
alpha',beta'-epoxyketone epoxomicin
Anticancer
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
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Antibacterial
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Anti-Gram-negative
Antimicrobial
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Antibacterial
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Anti-Gram-positive
Antimicrobial
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Antibiotic activity
Antimicrobial
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Antifungal
Antiparasitic
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Antimalarial
Antiparasitic
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Antiprotozoal
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Antimalarial
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Anti-Plasmodium
Antiparasitic
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General antiparasitic
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Antiparasitic
Enzyme modulation
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Enzyme inhibition
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Protease inhibition
Enzyme modulation
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Enzyme inhibition
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Proteasome inhibitor
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Venom / Toxin
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General toxin
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Toxic
Venom / Toxin
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General toxin
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Toxin
not Standard
3 amino acids
-
contains X representing unresolved or non-standard residue
XXX
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0107111
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
CH3(CH2)8CO
Amidation
Ornithine at 1,2,3; Ornithine
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Anti-Gram-positive
Anti-Gram-negative
Cryptococcus neoformans ATCC 2344
100 μg/mL
RECORD: Rec_0111967
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
CH3(CH2)16CO
Amidation
Ornithine at 1,2,3; Ornithine
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Anti-Gram-positive
Anti-Gram-negative
Staphylococcus aureus MTCC 3160
6.25 μg/mL
RECORD: Rec_0112624
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
CH3(CH2)14CO
Amidation
Ornithine at 1,2,3; Ornithine
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Anti-Gram-positive
Anti-Gram-negative
Bacillus subtilis MTCC 2763
12.5 μg/mL
RECORD: Rec_0114216
VERIFIED: NO
Provenance & Taxonomy
not reported [other]
unknown
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Non-proteinogenic/modified monomers: 3hb; Fch; 4os
Bio-Activity Profile
-
RECORD: Rec_0114310
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
ornithine at 1,2; unspecified non-canonical residue at 3
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Escherichia coli
3.5
MIC
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