MYP_004938
alpha',beta'-epoxyketone epoxomicin
Anticancer
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
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Antibacterial
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Anti-Gram-negative
Antimicrobial
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Antibacterial
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Anti-Gram-positive
Antimicrobial
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Antibiotic activity
Antimicrobial
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Antifungal
Antiparasitic
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Antimalarial
Antiparasitic
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Antiprotozoal
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Antimalarial
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Anti-Plasmodium
Antiparasitic
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General antiparasitic
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Antiparasitic
Enzyme modulation
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Enzyme inhibition
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Protease inhibition
Enzyme modulation
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Enzyme inhibition
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Proteasome inhibitor
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Venom / Toxin
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General toxin
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Toxic
Venom / Toxin
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General toxin
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Toxin
not Standard
3 amino acids
-
contains X representing unresolved or non-standard residue
XXX
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0385287
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
-NH2
Ornithine at 1,2; unspecified non-canonical residue at 3; Ornithine
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Staphylococcus aureus
>227.2
MIC
RECORD: Rec_0385601
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Contains non-standard or unspecified residue(s): X; Conjugate type: amide; Conjugated small molecule: 2-[(11aS)-1,3,4,11a-tetrahydro-6-oxo-2H-benzo[b]quinolizin-11(6H)-ylidene]-, (2Z)-acetic acid
Bio-Activity Profile
-
RECORD: Rec_0390425
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
CH3(CH2)10CO
Amidation
Ornithine at 1,2,3; Ornithine
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Anti-Gram-positive
Anti-Gram-negative
Staphylococcus aureus MTCC 3160
3.1 μg/mL
RECORD: Rec_0390500
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
CH3(CH2)12CO
Amidation
Ornithine at 1,2,3; Ornithine
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Anti-Gram-positive
Anti-Gram-negative
Bacillus subtilis MTCC 2763
6.25 μg/mL
RECORD: Rec_0391487
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
ornithine at 1,2; unspecified non-canonical residue at 3
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Enterococcus faecalis
7.1
MIC
Showing 5 records on this page · Page 23 of 26