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MYP_004927
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Basic Information
C18-c03
Antimicrobial
Antiviral
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza A ▸ Anti-H1N1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Enzyme modulation ▸ Enzyme inhibition ▸ Binding inhibition
Standard
15 amino acids
C74H116N26O20
Standard
Sequence
RAVWRHSVATPSHSV
Physicochemical Analysis
1689.88 Da
12.00
1.93
1.63
0.1290
-0.32
0.38
-0.07
35.01
71.33
0.0667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
739.80
-8.76
28.0
24.0
49.0
120.0
5.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0058530 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Library-derived peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
Influenza A virus (Virus entry); B16
6.5 μM
Plaque assay
PaperInhibition of influenza virus infections by sialylgalactose-binding peptides selected from a phage library. | Matsubara T, Sumi M, Kubota H, Taki T, Okahata Y, Sato T. | J Med Chem. 2009 | PMID:19558186 PMID19558186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19558186/
RECORD: Rec_0060800 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Alkylated(C18)
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
H3N2(A/Aichi/2/68):inhibition of virus infection in Madin-Darby canine kidney(MDCK) cells
68 μM
IC50
PaperPubMed PMID: 19558186 PMID19558186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19558186/
RECORD: Rec_0072273 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
H1N1(A/PR/8/34):inhibition of virus infection in Madin-Darby canine kidney(MDCK) cells
500 μM
IC50
PaperPubMed PMID: 19558186 PMID19558186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19558186/
RECORD: Rec_0098311 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Library-derived peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
Influenza A virus (Virus entry); B16
500 μM
Plaque assay
PaperInhibition of influenza virus infections by sialylgalactose-binding peptides selected from a phage library. | Matsubara T, Sumi M, Kubota H, Taki T, Okahata Y, Sato T. | J Med Chem. 2009 | PMID:19558186 PMID19558186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19558186/
RECORD: Rec_0149416 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 19558186 PMID19558186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19558186/
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