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MYP_004911
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Basic Information
Ocellatin-PT5
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
25 amino acids
C119H200N34O33S
Standard
Sequence
GVFDIIKDAGRQLVAHAMGKIAEKV
Physicochemical Analysis
2667.13 Da
8.50
0.85
0.59
0.0340
0.29
0.76
0.13
5.26
113.20
0.0400
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1085.35
-8.15
37.0
36.0
93.0
187.0
2.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0184357 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pustulatus [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes (4% Hemolysis at 800 microg/ml
800 μg/mL
Hemolysis
PMID26107622;27463422;29308671 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26107622/
RECORD: Rec_0187696 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pustulatus [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Pseudomonas aeruginosa PAO1
512 μg/mL
MIC
PMID26107622;27463422;29308671 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26107622/
RECORD: Rec_0223795 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pustulatus [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Leishmania infantum MHOM/MA/67/ITMAP-263
62.72 μg/mL
IC50
PMID26107622;27463422;29308671 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26107622/
RECORD: Rec_0291985 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pustulatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic Anti-Gram-negative
Escherichia coli
300 μM
MIC
RECORD: Rec_0350944 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pustulatus [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Pseudomonas aeruginosa Pa1-SA2
256 μg/mL
MIC
PMID26107622;27463422;29308671 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26107622/
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