Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC357H577N107O111S10

DescriptionStandard

        MEKKSIAGLCFLFLVLFVAQEVVVQSEAKTCENLADTYRGPCFTTGSCDDHCKNKEHLLSGRCRDDVRCRCTRNC
    

Molecular Weight8464.70 Da

Isoelectric Point (pI)7.51

Net Charge (pH 7.0)0.60

Net Charge (pH 7.4) 0.13

Charge Density (pH 7.0) 0.0080

GRAVY Index-0.23

Hydrophobic Moment 0.56

Boman Index-0.11

Instability Index26.88

Aliphatic Index 70.13

Aromaticity 0.0667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3557.54

LogP -40.39

H-bond Donors 134.0

H-bond Acceptors 124.0

Rotatable Bonds 286.0

Heavy Atoms 585.0

Ring Count 8.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0236990 VERIFIED: NO

Provenance & Taxonomy

OrganismVigna mungo [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Non-hemolytic Non-ribosomal