Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length65 amino acids

Chemical FormulaC355H549N95O86S8

DescriptionStandard

        MKIHLFLFILLFWVTILPAKKRYPEYGSLDLRWECRMSKGHCKTQCSENEFRIAFCIRPGTHCCI
    

Molecular Weight7780.26 Da

Isoelectric Point (pI)9.08

Net Charge (pH 7.0)4.71

Net Charge (pH 7.4) 4.24

Charge Density (pH 7.0) 0.0724

GRAVY Index0.05

Hydrophobic Moment 0.48

Boman Index0.05

Instability Index53.09

Aliphatic Index 85.54

Aromaticity 0.1385

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2891.09

LogP -17.17

H-bond Donors 109.0

H-bond Acceptors 102.0

Rotatable Bonds 254.0

Heavy Atoms 544.0

Ring Count 17.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0319626 VERIFIED: NO

Provenance & Taxonomy

OrganismPeromyscus maniculatus bairdii [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence