MYP_004830
TAT-analogue
Anticancer
Delivery / Targeting
▸
Cell penetration
▸
Cell-penetrating peptide
Delivery / Targeting
▸
Drug delivery vehicle
Standard
14 amino acids
C76H143N37O17
Standard
KGRKKRRQRRRPPQ
1847.19 Da
12.00
8.76
8.55
0.6255
-3.52
0.48
-1.48
204.28
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
959.68
-12.16
36.0
26.0
67.0
130.0
2.0
15.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0179401
VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: 5-FAM (Hydroxyfluorescein) dye
Bio-Activity Profile
Anticancer
RECORD: Rec_0263235
VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Doxorubicin is attached by a cathepsin B degradable tetrapeptide linker (-Gly-Phe-Leu-Gly-).
Bio-Activity Profile
Cargo delivery