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MYP_004827
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Basic Information
Halictine 2 (bees,insects,animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
12 amino acids
C69H116N18O14S
Standard
Sequence
GKWMSLLKHILK
Physicochemical Analysis
1453.84 Da
10.30
2.84
2.59
0.2370
0.07
0.64
0.12
96.96
130.00
0.0833
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
526.18
-0.63
19.0
19.0
51.0
102.0
3.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0268162 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Halictus sexcinctus [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Bacillus subtilis, Staphylococcus aureus, Escherichia coli
0.8-7.7 μM
MIC
PaperNovel antimicrobial peptides from the venom of the eusocial bee Halictus sexcinctus (Hymenoptera: Halictidae) and their analogs
RECORD: Rec_0271852 VERIFIED: YES
Provenance & Taxonomy
Halictus sexcinctus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
42.1 μM
MIC
PMID20198492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20198492/
RECORD: Rec_0272947 VERIFIED: YES
Provenance & Taxonomy
Insecta [Animal]
50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperToxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells PMID22100226 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100226/
RECORD: Rec_0276931 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Halictine
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
PMID20198492;18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20198492/
RECORD: Rec_0291124 VERIFIED: YES
Provenance & Taxonomy
Halictus sexcinctus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
Candida tropicalis ATCC 750
1.6 μM
MIC
PMID30753486 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30753486/
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