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MYP_004827
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Basic Information
Halictine 2 (bees,insects,animals)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
12 amino acids
C69H116N18O14S
Standard
Sequence
GKWMSLLKHILK
Physicochemical Analysis
1453.84 Da
10.30
2.84
2.59
0.2370
0.07
0.64
0.12
96.96
130.00
0.0833
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
526.18
-0.63
19.0
19.0
51.0
102.0
3.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0148983 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
C. dubliniensis CD36
PMID28600071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28600071/
RECORD: Rec_0169216 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0183537 VERIFIED: YES
Provenance & Taxonomy
Halictus sexcinctus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID20198492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20198492/
RECORD: Rec_0190382 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
Saccharomyces cerevisiae BY4741
PMID28600071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28600071/
RECORD: Rec_0197795 VERIFIED: YES
Provenance & Taxonomy
Halictus sexcinctus [Animal]
Halictine
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Anticancer Cytotoxic Anti-mammalian cells
PaperAmino Acids. 2010 Aug;39(3):763-75. PubMed. | http://www.ncbi.nlm.nih.gov/pubmed/20198492 PMID20198492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20198492/
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