Peptide Database

Peptide NameEsculentin-2P (Frogs, amphibians, animals)

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor cross

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC176H296N50O45S2

DescriptionStandard

        GFLSIFRGVAKFASKGLGKDLARLGVNLVACKISKQC
    

Molecular Weight3896.67 Da

Isoelectric Point (pI)10.21

Net Charge (pH 7.0)5.74

Net Charge (pH 7.4) 5.50

Charge Density (pH 7.0) 0.1550

GRAVY Index0.48

Hydrophobic Moment 0.75

Boman Index0.13

Instability Index16.78

Aliphatic Index 108.11

Aromaticity 0.0811

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1548.99

LogP -14.27

H-bond Donors 57.0

H-bond Acceptors 53.0

Rotatable Bonds 136.0

Heavy Atoms 273.0

Ring Count 3.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0233283 VERIFIED: YES

Provenance & Taxonomy

OrganismRana pipiens [Animal]

FamilyEsculentin

Structure & Mods

Configside-chain cyclized peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermCyclization

Disulfide31-37

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetFrog Virus 3

FIRST PREV 1 2

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