Peptide Database

Peptide NameHuman beta defensin 2

Function Ontology

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Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC190H317N61O46S6

DescriptionStandard

        IRNPVTCLRSGAICHPGFCPRRYKHIGICGVSAIKCCKKP
    

Molecular Weight4384.32 Da

Isoelectric Point (pI)9.77

Net Charge (pH 7.0)7.87

Net Charge (pH 7.4) 7.47

Charge Density (pH 7.0) 0.1968

GRAVY Index0.03

Hydrophobic Moment 0.61

Boman Index-0.03

Instability Index60.95

Aliphatic Index 78.00

Aromaticity 0.0500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1696.11

LogP -17.00

H-bond Donors 66.0

H-bond Acceptors 62.0

Rotatable Bonds 140.0

Heavy Atoms 303.0

Ring Count 8.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0148975 VERIFIED: YES

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyDefensin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)