Peptide Database

Peptide NameLysozyme A (EC 3.2.1.n3) (1;4-beta-N-acetylmuramidase A)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length181 amino acids

Chemical FormulaC857H1304N218O262S21

DescriptionStandard

        MRIAFFLLVLAVIIGFAYGYSCPKPCYGNMCCSTSPNNQYYLTDFCGSTSACGPVPSCSGALYFTADSQRFGCGKYLNLCRSGKCVKAQIYDAGPAMWVEQDAGMMIIDASPTICHVLTGGSSCGWSDHFLITATVTSLTDSRPLGPFNVTESEMAQLFIDHEIAMAQCEAEKTCNGFDLE
    

Molecular Weight19526.19 Da

Isoelectric Point (pI)4.77

Net Charge (pH 7.0)-7.35

Net Charge (pH 7.4) -7.97

Charge Density (pH 7.0) -0.0406

GRAVY Index0.19

Hydrophobic Moment 0.47

Boman Index0.19

Instability Index40.73

Aliphatic Index 71.22

Aromaticity 0.1105

Extinction Coeff. Reduced 22920.00

Extinction Coeff. Oxidized 23795.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7559.69

LogP -81.20

H-bond Donors 273.0

H-bond Acceptors 279.0

Rotatable Bonds 620.0

Heavy Atoms 1358.0

Ring Count 34.0

Amide Bonds 192.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0007883 VERIFIED: YES

Provenance & Taxonomy

OrganismDictyostelium discoideum [Fungus]

FamilyDictyostelium lysozyme

Tax ID44689

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriolytic enzyme Anti-Gram-positive Glycosidase Hydrolase Non-hemolytic

TargetB. megaterium

RECORD: Rec_0205120 VERIFIED: YES

Provenance & Taxonomy

OrganismDictyostelium discoideum [Fungus]

FamilyDictyostelium lysozyme

Tax ID44689

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriolytic enzyme Anti-Gram-positive Glycosidase Hydrolase Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0311346 VERIFIED: YES

Provenance & Taxonomy

OrganismDictyostelium discoideum [Fungus]

FamilyDictyostelium lysozyme

Tax ID44689

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriolytic enzyme Anti-Gram-positive Glycosidase Hydrolase Non-hemolytic

TargetBacillus subtilis (Gram-positive)