Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC245H415N71O80S7

DescriptionStandard

        MSTKDFNLDLVSVSKKDSGASPRITSISLCTPGCKTGALMGCAAKTATCHCSIHVSK
    

Molecular Weight5859.80 Da

Isoelectric Point (pI)8.99

Net Charge (pH 7.0)3.62

Net Charge (pH 7.4) 3.22

Charge Density (pH 7.0) 0.0636

GRAVY Index0.09

Hydrophobic Moment 0.31

Boman Index0.05

Instability Index35.11

Aliphatic Index 71.93

Aromaticity 0.0175

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2409.16

LogP -33.64

H-bond Donors 91.0

H-bond Acceptors 93.0

Rotatable Bonds 196.0

Heavy Atoms 403.0

Ring Count 5.0

Amide Bonds 57.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0199689 VERIFIED: NO

Provenance & Taxonomy

OrganismLactococcus lactis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence

RECORD: Rec_0367376 VERIFIED: NO