Peptide Database

Peptide NameCyclotide viba 9

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC136H222N38O39S6

DescriptionStandard

        GIPCGESCVWIPCISSAIGCSCKNKVCYRK
    

Molecular Weight3205.84 Da

Isoelectric Point (pI)8.66

Net Charge (pH 7.0)2.70

Net Charge (pH 7.4) 2.40

Charge Density (pH 7.0) 0.0900

GRAVY Index0.34

Hydrophobic Moment 0.36

Boman Index0.12

Instability Index28.86

Aliphatic Index 74.67

Aromaticity 0.0667

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1226.93

LogP -13.51

H-bond Donors 49.0

H-bond Acceptors 48.0

Rotatable Bonds 102.0

Heavy Atoms 219.0

Ring Count 5.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0123684 VERIFIED: NO

Provenance & Taxonomy

OrganismViola tricolor [Plant]

FamilyCyclotide

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0246301 VERIFIED: YES

Provenance & Taxonomy

OrganismViola tricolor [Plant],Viola baoshanensis [Plant]

FamilyCyclotide

Tax ID214053;349688

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Antimicrobial

PaperIdentification of two suites of cyclotide precursor genes from metallophyte Viola baoshanensis: cDNA sequence variation, alternative RNA splicing and potential cyclotide diversity | Peptidomics of Circular Cysteine-Rich Plant Peptides: Analysis of the Diversity of Cyclotides from Viola tricolor by Transcriptome and Proteome Mining Evidence URLhttps://www.uniprot.org/uniprotkb/B5B3Y6/entry

RECORD: Rec_0298417 VERIFIED: YES

Provenance & Taxonomy

OrganismViola baoshanensis [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)