Peptide Database

Peptide NameDefensin 7

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC439H723N121O136S9

DescriptionStandard

        MKTLVLLSALVLLALQVQAEPTPKTDEGTKTDEQPGKEDQVVSVSIEGQGDPAFQDGVLRDLKCFCRAKSCNWGEGIMGICNKRYGMLILCCR
    

Molecular Weight10160.75 Da

Isoelectric Point (pI)5.33

Net Charge (pH 7.0)-1.54

Net Charge (pH 7.4) -1.87

Charge Density (pH 7.0) -0.0166

GRAVY Index-0.10

Hydrophobic Moment 0.78

Boman Index0.02

Instability Index33.30

Aliphatic Index 90.11

Aromaticity 0.0430

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4145.51

LogP -41.70

H-bond Donors 146.0

H-bond Acceptors 144.0

Rotatable Bonds 346.0

Heavy Atoms 705.0

Ring Count 9.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0008427 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0417960 VERIFIED: YES