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MYP_004654
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Basic Information
Apo5 APOC164-88
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
25 amino acids
C145H220N38O38
Standard
Sequence
FSTKTRNWFSEHFKKVKEKLKDTFA
Physicochemical Analysis
3103.53 Da
10.00
3.85
3.58
0.1539
-1.15
0.59
-0.29
-7.50
31.20
0.2000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1280.35
-10.34
46.0
43.0
107.0
221.0
7.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0341424 VERIFIED: YES
Provenance & Taxonomy
Alligator mississippiensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 33592
0.0680 μg/mL
EC50
PMID27542832 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27542832/
RECORD: Rec_0370848 VERIFIED: YES
Provenance & Taxonomy
American alligator [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID27542832 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27542832/
RECORD: Rec_0376668 VERIFIED: YES
Provenance & Taxonomy
American alligator [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
Not hemolytic to sheep red blood cells
PMID27542832 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27542832/
RECORD: Rec_0382334 VERIFIED: YES
Provenance & Taxonomy
American alligator [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 4157
19.7 μg/mL
EC50
PMID27542832 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27542832/
RECORD: Rec_0388190 VERIFIED: YES
Provenance & Taxonomy
Alligator mississippiensis [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa
1.41 μM
EC50
PaperBioprospecting the American Alligator (Alligator mississippiensis) Host Defense Peptidome.
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