Peptide Database

Peptide NameChemokinostatin-5

Function Ontology

Anticancer

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC119H199N29O34S

DescriptionStandard

        NGKEICLDPEAPFLKKVIQKILD
    

Molecular Weight2612.09 Da

Isoelectric Point (pI)6.28

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.47

Charge Density (pH 7.0) -0.0106

GRAVY Index-0.17

Hydrophobic Moment 0.72

Boman Index0.01

Instability Index37.69

Aliphatic Index 118.70

Aromaticity 0.0435

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1025.40

LogP -5.83

H-bond Donors 33.0

H-bond Acceptors 35.0

Rotatable Bonds 90.0

Heavy Atoms 183.0

Ring Count 3.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0281108 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Anti-angiogenic Endothelial cell antiproliferative Endothelial cell antimigratory Anticancer Antimicrobial

Targethuman umbilical vein endothelial cells (HUVECs)

MethodHUVEC proliferation inhibition assay; HUVEC migration inhibition assay

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