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MYP_004653
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Basic Information
Chemokinostatin-5
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic
Standard
23 amino acids
C119H199N29O34S
Standard
Sequence
NGKEICLDPEAPFLKKVIQKILD
Physicochemical Analysis
2612.09 Da
6.28
-0.24
-0.47
-0.0106
-0.17
0.72
0.01
37.69
118.70
0.0435
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1025.40
-5.83
33.0
35.0
90.0
183.0
3.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0033538 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID18307172 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18307172/
RECORD: Rec_0049720 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Chemokinostatin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-angiogenic
Endothelial screening context
PaperSupporting Information for Karagiannis and Popel, PNAS (10.1073/pnas.0803241105) PMID18780781 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18780781/
RECORD: Rec_0088832 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Anti-angiogenic
PaperAntiAngioPred: A Server for Prediction of Anti-Angiogenic Peptides PMID26335203 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26335203/
RECORD: Rec_0151270 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Chemokinostatin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-angiogenic
Endothelial cells
Endothelial proliferation assay
PaperNovel anti-angiogenic peptides derived from ELR-containing CXC chemokines PMID18307172 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18307172/
RECORD: Rec_0151507 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID18307172 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18307172/
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