Peptide Database

Peptide NameSLAY-screened peptide P4982

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC109H164N24O31S3

DescriptionStandard

        YYLNCTPFMLQSTQIMKGTY
    

Molecular Weight2402.81 Da

Isoelectric Point (pI)8.15

Net Charge (pH 7.0)0.75

Net Charge (pH 7.4) 0.52

Charge Density (pH 7.0) 0.0373

GRAVY Index-0.10

Hydrophobic Moment 0.30

Boman Index0.17

Instability Index66.17

Aliphatic Index 58.50

Aromaticity 0.2000

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 904.33

LogP -6.92

H-bond Donors 32.0

H-bond Acceptors 35.0

Rotatable Bonds 75.0

Heavy Atoms 167.0

Ring Count 5.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0207727 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/