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MYP_004645
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Basic Information
P5
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
20 amino acids
C120H189N29O21
Standard
Sequence
KWKLFKKIGIGAFLHLAKKF
Physicochemical Analysis
2373.97 Da
10.70
5.84
5.58
0.2921
0.20
0.52
0.16
-14.99
107.50
0.2000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
816.81
0.33
29.0
28.0
83.0
170.0
6.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0145672 VERIFIED: YES
Provenance & Taxonomy
Ceropin A-Magainin 2 [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human red blood cells: hemolysis 1
PaperPubMed PMID: 9352466 PMID9352466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9352466/
RECORD: Rec_0188600 VERIFIED: YES
Provenance & Taxonomy
Ceropin A-Magainin 2 [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 9352466 PMID9352466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9352466/
RECORD: Rec_0214490 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
RECORD: Rec_0249747 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0279182 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
CA-MA / CA-ME / cecropin-magainin hybrid
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer
NCI-H128
2.9 μM
IC50 / MTT-MTS assay
PaperPMID 9352466; CA-MA/CA-ME analog P5 report PMID9352466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9352466/
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