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MYP_004645
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Basic Information
P5
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
20 amino acids
C120H189N29O21
Standard
Sequence
KWKLFKKIGIGAFLHLAKKF
Physicochemical Analysis
2373.97 Da
10.70
5.84
5.58
0.2921
0.20
0.52
0.16
-14.99
107.50
0.2000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
816.81
0.33
29.0
28.0
83.0
170.0
6.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006836 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Cecropin
8355
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial
NCI-H146
3.2 μM
IC50
PMID9352466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9352466/
RECORD: Rec_0019882 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Antibacterial Antimicrobial
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
RECORD: Rec_0047597 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Cecropin
8355
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial
NCI-H128
2.9 μM
IC50
PMID9352466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9352466/
RECORD: Rec_0108211 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin A-Magainin 2 hybrid peptides
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Antibacterial
NCI-H128 (lung cancer)
2.9 μM
IC50
PaperStructure-antitumor and hemolytic activity relationships of synthetic peptides derived from cecropin A-magainin 2 and cecropin A-melittin hybrid peptides | https://pubmed.ncbi.nlm.nih.gov/9352466/ PMID9352466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9352466/
RECORD: Rec_0144584 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Cecropin
8355
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial
NCI-H69
2.9 μM
IC50
PMID9352466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9352466/
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