Peptide Database

Peptide NameCecropin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC181H319N59O53

DescriptionStandard

        GLLKKIGKKLERVAQHTRDATLQGLEIAQKAANVAATAR
    

Molecular Weight4169.83 Da

Isoelectric Point (pI)10.55

Net Charge (pH 7.0)4.85

Net Charge (pH 7.4) 4.58

Charge Density (pH 7.0) 0.1243

GRAVY Index-0.34

Hydrophobic Moment 0.91

Boman Index-0.12

Instability Index12.40

Aliphatic Index 105.38

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1858.55

LogP -20.07

H-bond Donors 65.0

H-bond Acceptors 59.0

Rotatable Bonds 149.0

Heavy Atoms 293.0

Ring Count 1.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0157972 VERIFIED: YES

Provenance & Taxonomy

OrganismDrosophila rhopaloa [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)