Peptide Database

Peptide NameNeurotoxin PNTx13C3

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC143H230N44O44S9

DescriptionStandard

        VFCRSNGQQCTSDGQCCYGKCMTAFMGKICMR
    

Molecular Weight3558.21 Da

Isoelectric Point (pI)8.67

Net Charge (pH 7.0)2.67

Net Charge (pH 7.4) 2.37

Charge Density (pH 7.0) 0.0835

GRAVY Index-0.11

Hydrophobic Moment 0.40

Boman Index-0.05

Instability Index36.72

Aliphatic Index 24.38

Aromaticity 0.0938

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1452.07

LogP -19.38

H-bond Donors 57.0

H-bond Acceptors 56.0

Rotatable Bonds 120.0

Heavy Atoms 240.0

Ring Count 3.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0078646 VERIFIED: NO

Provenance & Taxonomy

OrganismPhoneutria nigriventer,Ctenus nigriventer [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3-17; 10-21; 16-30

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0340178 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic