Peptide Database

Peptide NameSLAY-screened peptide P1863

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC113H166N30O28S

DescriptionStandard

        CFDRPHNFINGIPFLRIYTT
    

Molecular Weight2424.78 Da

Isoelectric Point (pI)8.23

Net Charge (pH 7.0)0.84

Net Charge (pH 7.4) 0.57

Charge Density (pH 7.0) 0.0419

GRAVY Index-0.04

Hydrophobic Moment 0.57

Boman Index0.10

Instability Index27.67

Aliphatic Index 78.00

Aromaticity 0.2000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 935.29

LogP -6.48

H-bond Donors 33.0

H-bond Acceptors 31.0

Rotatable Bonds 72.0

Heavy Atoms 172.0

Ring Count 7.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0153282 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/