Peptide Database

Peptide NameTHP-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC178H286N50O46S6

DescriptionStandard

        GRKSDCFRKSGFCAFLKCPSLTLISGKCSRFYLCCK
    

Molecular Weight4054.87 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)6.70

Net Charge (pH 7.4) 6.40

Charge Density (pH 7.0) 0.1860

GRAVY Index0.07

Hydrophobic Moment 0.42

Boman Index-0.07

Instability Index30.11

Aliphatic Index 56.94

Aromaticity 0.1389

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1567.74

LogP -16.23

H-bond Donors 64.0

H-bond Acceptors 59.0

Rotatable Bonds 136.0

Heavy Atoms 280.0

Ring Count 6.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0365222 VERIFIED: YES

Provenance & Taxonomy

OrganismGallus gallus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)