Peptide Database

Peptide NameSLAY-screened peptide P3298

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC103H139N27O25

DescriptionStandard

        TTPSSYSPWRRWLHFFS
    

Molecular Weight2155.37 Da

Isoelectric Point (pI)10.83

Net Charge (pH 7.0)1.48

Net Charge (pH 7.4) 1.24

Charge Density (pH 7.0) 0.0873

GRAVY Index-0.81

Hydrophobic Moment 0.62

Boman Index-0.04

Instability Index124.77

Aliphatic Index 22.94

Aromaticity 0.2941

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 837.01

LogP -6.68

H-bond Donors 32.0

H-bond Acceptors 28.0

Rotatable Bonds 59.0

Heavy Atoms 155.0

Ring Count 10.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0049265 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/