Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length103 amino acids

Chemical FormulaC503H834N134O137S8

DescriptionStandard

        PLSLGKSVNMKLFLVLIVLLSQVLTAGAKPPRCFNNAAGYCKKRCKVGEISEMGCLHGKLCCVKEQKSKKYHKVQQLPPGPKSTAEKASDYIAYPTVTLVSIL
    

Molecular Weight11207.34 Da

Isoelectric Point (pI)9.61

Net Charge (pH 7.0)11.07

Net Charge (pH 7.4) 10.79

Charge Density (pH 7.0) 0.1075

GRAVY Index0.02

Hydrophobic Moment 0.56

Boman Index0.06

Instability Index22.45

Aliphatic Index 96.50

Aromaticity 0.0583

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4322.04

LogP -38.73

H-bond Donors 154.0

H-bond Acceptors 158.0

Rotatable Bonds 378.0

Heavy Atoms 782.0

Ring Count 15.0

Amide Bonds 109.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0278912 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence