Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length196 amino acids

Chemical FormulaC976H1552N268O270S9

DescriptionStandard

        PKTPPMAHESMLLLAVTELVANSAAFTYFTAGALRRNFSSDMLPRKFPLQLRTKSMEVFSPELQERYPDQPMELHLWARQQPLLSCHPDALHGSLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGLVPNPELAQTSPPALCRAQDLPVPQVKRLETLLKFGLWLFGVPQANSKCCSHPVL
    

Molecular Weight21648.98 Da

Isoelectric Point (pI)9.28

Net Charge (pH 7.0)5.38

Net Charge (pH 7.4) 4.98

Charge Density (pH 7.0) 0.0274

GRAVY Index-0.05

Hydrophobic Moment 0.55

Boman Index0.07

Instability Index53.77

Aliphatic Index 92.09

Aromaticity 0.0714

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8469.12

LogP -106.36

H-bond Donors 290.0

H-bond Acceptors 289.0

Rotatable Bonds 687.0

Heavy Atoms 1523.0

Ring Count 42.0

Amide Bonds 212.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0227178 VERIFIED: NO

Provenance & Taxonomy

OrganismBrachypodius atriceps [Plant]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria