Peptide Database

Peptide NameCycloviolacin O5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC126H203N33O37S6

DescriptionStandard

        PCGESCVWIPCISAVVGCSCKSKVCYKN
    

Molecular Weight2964.55 Da

Isoelectric Point (pI)8.46

Net Charge (pH 7.0)1.90

Net Charge (pH 7.4) 1.75

Charge Density (pH 7.0) 0.0678

GRAVY Index0.52

Hydrophobic Moment 0.28

Boman Index0.18

Instability Index21.94

Aliphatic Index 72.86

Aromaticity 0.0714

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1101.63

LogP -12.23

H-bond Donors 45.0

H-bond Acceptors 45.0

Rotatable Bonds 93.0

Heavy Atoms 202.0

Ring Count 5.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0137487 VERIFIED: YES

Provenance & Taxonomy

OrganismViola odorata [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)