Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length292 amino acids

Chemical FormulaC1435H2279N385O426S12

DescriptionStandard

        MTSCVFSLFFLLSLCSSITADGPTGLKVRITDKATELLKDLGLKFLKELIKKPFEDFQLLTCHIKRLTLTRLDMNPNDVNIRFQPGSGLQFEFKDLNGTAEIERGTNRCFLNIFQGTAVVTGQNVGVTIGVRLIQTGGRLSLEIPSGDDYCKTRADRIRVDNFRFVVNAALTAALRFMFTSQFCPDIRNLVPNVNTMLAGVAMTRTLSKDHKINLDYSLSGNVTVTSNSLDVPFTGVVYYGDTRPALPAAGVVPVFTESNQMAYVGVSEDLFKSAGQALYDHGPFDLTVPQD
    

Molecular Weight32125.55 Da

Isoelectric Point (pI)6.82

Net Charge (pH 7.0)-0.27

Net Charge (pH 7.4) -0.78

Charge Density (pH 7.0) -0.0009

GRAVY Index0.04

Hydrophobic Moment 0.75

Boman Index0.08

Instability Index27.84

Aliphatic Index 93.42

Aromaticity 0.0890

Extinction Coeff. Reduced 8940.00

Extinction Coeff. Oxidized 9315.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0425942 VERIFIED: NO

Provenance & Taxonomy

OrganismPerca fluviatilis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria