Peptide Database

Peptide NameChromogranin A-derived peptide, WE-14

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Hormonal / Endocrine ▸ Hormone peptide

Hormonal / Endocrine ▸ Secretory pathway peptide ▸ Secretory granule peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC73H120N20O23S

DescriptionStandard

        WSKMDRLAKELTAE
    

Molecular Weight1677.92 Da

Isoelectric Point (pI)6.30

Net Charge (pH 7.0)-0.23

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0164

GRAVY Index-0.86

Hydrophobic Moment 0.69

Boman Index-0.24

Instability Index27.19

Aliphatic Index 70.00

Aromaticity 0.0714

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 723.71

LogP -5.59

H-bond Donors 26.0

H-bond Acceptors 24.0

Rotatable Bonds 58.0

Heavy Atoms 117.0

Ring Count 2.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0155627 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

RECORD: Rec_0260377 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyWE

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Receptor modulation Immunomodulatory

Targetcells and noradrenergic neurons

Half-LifeMammalian: 2.8 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0366059 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyWE

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Receptor modulation Immunomodulatory

Half-LifeMammalian: 2.8 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0386003 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyChromogranin/secretogranin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Secretory granule peptide Neuropeptide precursor