Peptide Database

Peptide NameIFN-α21

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length166 amino acids

Chemical FormulaC859H1354N234O256S8

DescriptionStandard

        CDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFGFPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLEACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKIFQERLRRKE
    

Molecular Weight19311.87 Da

Isoelectric Point (pI)5.99

Net Charge (pH 7.0)-1.98

Net Charge (pH 7.4) -2.44

Charge Density (pH 7.0) -0.0119

GRAVY Index-0.37

Hydrophobic Moment 0.62

Boman Index-0.06

Instability Index55.96

Aliphatic Index 85.18

Aromaticity 0.0964

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8005.84

LogP -79.79

H-bond Donors 278.0

H-bond Acceptors 265.0

Rotatable Bonds 659.0

Heavy Atoms 1357.0

Ring Count 26.0

Amide Bonds 185.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0016023 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsPredicted disulphide bond formation between cysteine residues at positions 1 and 99, and 29 and 139

Bio-Activity Profile

Function

Receptor agonist Signaling peptide

TargetInterferon-α/β receptor (Human)