Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length534 amino acids

Chemical FormulaC2655H4243N709O744S24

DescriptionStandard

        MARGPCNAPRWASLLVLVVMSTAVAAAINPGVVVRISQKGLDYAAQQGTAVLQKELERIKIPDYSGSFKIKHLGKGHYSFYRKTSGRFDLSIEGMSISADLKLGSNLTSGKPTVTCSSCSSHISSVHVHISNSKVGWLIRLFHKKIESALQNKLNSQVCQEVTSSVSSKLQPYLQTLPVMTKIDAVAGINYGLVAPPTTTAETLDVQMKGEFYRLNHHNPPPFAPPVMEFPAAHDRMVYLGLSDYFFNTAGLVYQEAGVLKMTLTDDMIPKESKFRLTTKFFGSFLPEVAKMFPNMKIQIHISASAPPQLSIQPTGLSFFPALDIQAFAVLANSSLASLFLIGMSTHGSLEVGVRSDRLVGELKVDRLLLELKHSNIGPFPVELLQDIMNYIIPTLVLPRVNEKLQKGFPLPMPARVQLYNMVLQSHQVSSRVSFPQSPLTIVTSSSPLLQCFLHAKPCVKRFLPLPQPWDVGAVNKQRRKIKIQKSHTVSNEVQIQSQSPGCEPSLPLPTLQSAKMKCADGPKSLFYKVHLSI
    

Molecular Weight58768.95 Da

Isoelectric Point (pI)9.58

Net Charge (pH 7.0)21.84

Net Charge (pH 7.4) 20.58

Charge Density (pH 7.0) 0.0409

GRAVY Index0.00

Hydrophobic Moment 0.67

Boman Index0.10

Instability Index51.74

Aliphatic Index 95.45

Aromaticity 0.0749

Extinction Coeff. Reduced 35870.00

Extinction Coeff. Oxidized 36370.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0352090 VERIFIED: NO

Provenance & Taxonomy

OrganismCallithrix jacchus [Animal]

FamilyBPI/LBP

Tax ID9483

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence