‹ ›
MYP_004252
← PREVIOUS NEXT → BACK
Basic Information
FIV Egp (732-766)
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Anti-Retrovirus ▸ Anti-Lentivirus ▸ Anti-FIV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition
Standard
35 amino acids
C188H292N50O59S
Standard
Sequence
LGEWYNQTKDLQQKFYEIIMDIEQNNVQGKKGIQQ
Physicochemical Analysis
4228.69 Da
4.94
-1.24
-1.45
-0.0353
-1.11
0.59
-0.14
44.87
75.14
0.1143
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1850.68
-16.75
59.0
59.0
150.0
298.0
5.0
44.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0251286 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antiviral Entry inhibition
inhibition of virus infection in FCD4-E cells
0.177 μM
EC90
Mammalian: 5.5 h; Yeast: 3 min; E. coli: 2 min
PaperC-Terminal gp40 peptide analogs inhibit feline immunodeficiency virus: cell fusion and virus spread. | Medinas RJ, Lambert DM, Tompkins WA. | J Virol. 2002 Sep;76(18):9079-86. | DOI:10.1128/jvi.76.18.9079-9086.2002 | PMID:12186891 PMID12186891 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12186891/
RECORD: Rec_0269173 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antiviral Anti-FIV Fusion inhibition
Feline immunodeficiency virus (FIV) | FIV/CrFK cells; HeLa cells
0.05 μM
EC50
Mammalian: 5.5 h; Yeast: 3 min; E. coli: 2 min
PaperC-Terminal gp40 peptide analogs inhibit feline immunodeficiency virus: cell fusion and virus spread. | Medinas RJ, Lambert DM, Tompkins WA. | J Virol. 2002 Sep;76(18):9079-86. | DOI:10.1128/jvi.76.18.9079-9086.2002 | PMID:12186891 PMID12186891 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12186891/
RECORD: Rec_0309321 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
Feline immunodeficiency virus (FIV):inhibition of cell-cell fusion between FIV/CrFK cells and HeLa cells
0.05 μM
EC50
PaperPubMed PMID: 12186891 PMID12186891 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12186891/
RECORD: Rec_0334263 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
inhibition of virus infection in FCD4-E cells
0.098 μM
EC50
PaperPubMed PMID: 12186891 PMID12186891 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12186891/
RECORD: Rec_0416882 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
HIV-1:inhibition of cell-cell fusion between CEM4/IIIb cells and MOLT4 cells
1.933 μM
EC50
PaperPubMed PMID: 12186891 PMID12186891 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12186891/
FIRST PREV 1 2 3
Showing 5 records on this page · Page 3 of 3