Peptide Database

Peptide NameGly8-GLP-1(7-36)(Glucagon Like protein-1)

Function Ontology

Binding / Molecular interaction ▸ Binding activity

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC140H213N35O44

DescriptionStandard

        EGTFTSDVSSYLEGQAAKEFIAWLVKGR
    

Molecular Weight3090.40 Da

Isoelectric Point (pI)4.87

Net Charge (pH 7.0)-1.16

Net Charge (pH 7.4) -1.34

Charge Density (pH 7.0) -0.0414

GRAVY Index-0.20

Hydrophobic Moment 0.48

Boman Index0.08

Instability Index18.24

Aliphatic Index 73.21

Aromaticity 0.1429

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1292.42

LogP -12.36

H-bond Donors 46.0

H-bond Acceptors 43.0

Rotatable Bonds 102.0

Heavy Atoms 219.0

Ring Count 5.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0134460 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGLP-1

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Receptor-binding

MethodEC50

Half-LifeRat Plasma, in vitro; 2160 s

RECORD: Rec_0325434 VERIFIED: YES