Peptide Database

Peptide NameBeta-defensin 5 (BD-5) (Defensin; beta 5)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length63 amino acids

Chemical FormulaC313H504N88O78S7

DescriptionStandard

        MRIHYLLFSFLLVLLSPLSVFTQSINNPVSCVTHGGICWGRCPGSFRQIGTCGLGKVRCCKKK
    

Molecular Weight6972.35 Da

Isoelectric Point (pI)9.77

Net Charge (pH 7.0)7.61

Net Charge (pH 7.4) 7.20

Charge Density (pH 7.0) 0.1208

GRAVY Index0.43

Hydrophobic Moment 0.50

Boman Index0.16

Instability Index38.71

Aliphatic Index 97.30

Aromaticity 0.0952

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2640.64

LogP -23.92

H-bond Donors 100.0

H-bond Acceptors 95.0

Rotatable Bonds 227.0

Heavy Atoms 486.0

Ring Count 12.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0007523 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyBeta-defensin; Defensin

Tax ID10116

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic